| Postgrad Med J 1998 Jul;74(873):391-4
The potential role of soluble fibre in the
treatment of hypercholesterolaemia.
Imperial College of Science, Technology and Medicine, National
Heart and Lung Institute, London, UK.
The three major modifiable coronary risk factors are smoking,
hypertension, and hypercholesterolaemia. Serum cholesterol levels
are above the desirable level of 5.2 mmol/l in 79% of men and
65% of women aged between 35 and 50 years and thus are an important
target for intervention. In this paper, the role of nonpharmacological
intervention with soluble fibre in treating mild to moderate
primary hypercholesterolaemia is reviewed. Evidence from controlled
studies shows that soluble fibre can be effective in lowering
cholesterol by clinically significant amounts. It is stressed,
however, that risk factors for coronary heart disease are interactive
and attention is shifting to addressing multiple rather that