SH, firstname.lastname@example.org; Joffe, DJ, email@example.com
Source: Diabetes In Control Newsletter,
Issue 15 (1) : 12-18 2000 Aug
OBJECTIVE: The prevalence
of diabetes has increased dramatically in recent years1.
However, the role of dietary fiber in blood glucose regulation
remains unclear. The purpose
of this work was to investigate the acute effects of supplementing
the diet with soluble fiber in regards to it’s glucose and cholesterol
lowering thereby reducing the HbA1c and therefore the complications
the HbA1c (Average Blood Glucose) 1%, the DCCT2 study showed Type 1 diabetics could
reduce the complications of Retinopathy
by 38%, Nephropathy by 28% Neuropathy by 35%.
The UKPDS3 showed that by reducing the HbA1c
in Type 2 diabetics by 0.9% you could reduce any diabetic end
point by 12%, reduce any Microvascular end point by 25%, reduce
MI by 16%, reduce Retinopathy by 21% and reduce microalbuminurea
at 12 years by 34%.
The UKPDS also
showed that Postprandial (blood glucose 1-2 hours after eating)
glucose is a better indicator of glycemic control than fasting
glucose levels4. Treatment
of postprandial hyperglycemia is critical to achieving optimal
outcomes in type 2 diabetes5.
The New England
JM6 5/2000 showed
that a high intake of dietary fiber 50 gms particularly
of the soluble type, improves glycemic control, decreases hyperinsulinemia,
and lowers plasma lipid concentrations in patients with type 2
After 30 days
of monitoring fasting and postprandial blood glucose, a base HbA1c
(9.2%), cholesterol screen-total cholesterol (210), Triglycerides
(299), HDL (35), weight (208lbs.)and blood pressure(145/82), Average
Postprandial blood glucose(250mg/dl.), average fasting blood glucose
(150mg/dl.) were taken. Fifteen
patients (7male/8 female), average age 65, were given 10grams
of soluble fiber to be added to their diet of 15-20 grams.
Fiber consisted of Guar Gum, Gum Arabic, Locust Bean Gum,
Pectin, Oat Fiber (Source of Beta Glucans), and Stevia dispersed
in Calcium Carbonate. Five grams were taken twice daily
5-10 minutes prior to eating for 90 days. They continued to monitor fasting
and postprandial blood glucose through the study period. At the conclusion of the 90 day
period, their levels were measured.
the fiber diet and supplementation was excellent. During the 12
weeks of the high-fiber diet and supplementation, mean daily preprandial
plasma glucose concentrations were 17 percent lower (95 percent
confidence interval). The
high-fiber diet and supplementation also lowered the area under
the curve for 2-hour plasma glucose concentrations, by 36 percent.
The high-fiber diet and supplementation reduced plasma total cholesterol
concentrations by 12 percent, triglyceride concentrations by 42
percent, raised high-density lipoprotein cholesterol concentrations
by 6 percent, reduced body weight by an average of 6 pounds, lowered
blood pressure from 145/82 to 131/77 and lowered HbA1c from 9.2%
to 7.8%(1.4 decrease).
A high intake
of dietary fiber, particularly of the soluble type, above the
level recommended by the ADA (25-30grm.), improves glycemic control,
decreases hyperinsulinemia, and lowers plasma lipid concentrations
in patients with type 2 diabetes. Reducing postprandial blood
glucose significantly caused a decrease of HbA1c by 1.4%, therefore
reducing the complications from diabetes. 2-5-6
1-Beckles GLA et al. Diabetes Care. 1998;21:1432-1438.American
Diabetes Association. Diabetes Care. 1998;21(Suppl 1).Colwell
JA. Ann Intern Med. 1996;124(1pt2):131-135.Abraira C et al. Diabetes
Care. 1992;15:1560-1571.Klein R et al. Am J Epidemiol.
CC et al. Diabetes
in America. 2nd ed.vol. 44, November ol. 44, November,
The New England
Journal of Medicine -- September 30, 1993 -- Vol. 329, No. 14-DCCT
research group, Diabetes 95;44:969-983;
Med J 2000
Jul;59(7):295-8, 313; BMJ. 2000 Aug 12;321(7258):405-12.
4. Harris et
al. Diabetes Care. 1994.
5- De Veciana
et al. N Engl J Med. 1995;333:1239
6- NEJM May
11, 2000 - Vol. 342, No. 19; Klein, R, Diabetes Care. 1996:18:258-268
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(For complete Study – www.diabetesincontrol.com