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| Curr Opin Lipidol 2001 Feb;12(1):35-40 |
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Soluble
fiber and nondigestible carbohydrate effects on plasma lipids
and cardiovascular risk.
Fernandez ML.
Department of Nutritional Sciences, The University of Connecticut,
Storrs, Connecticut 06269, USA. maria-luz.fernandez@uconn.edu
The association between elevated plasma LDL-cholesterol concentrations
and increased risk for heart disease has made the scientific
community aware of dietary sources that might effectively reduce
plasma cholesterol levels. Several large-scale cohort studies
have documented that dietary fiber lowers the risk for coronary
heart disease. In addition, there is substantial evidence from
randomized controlled clinical trials that a mean reduction
of 9% in LDL-cholesterol can be achieved by intake of different
sources of soluble fiber. Incorporating fiber sources into our
diet may provide a useful adjunct to a low-saturated fat diet,
and may have a further beneficial effect for individuals who
have mild-to-moderate hypercholesterolemia. The physicochemical
properties of soluble fiber result in important modifications
in volume, bulk and viscosity in the intestinal lumen, which
will alter metabolic pathways of hepatic cholesterol and lipoprotein
metabolism, resulting in lowering of plasma LDL-cholesterol.
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