Dietary fiber in the dietetic therapy of diabetes
mellitus. Experimental data with purified glucomannans
Riv Eur Sci Med Farmacol. 1992 Nov-Dec;14(6):367-73. [Article in Italian]
Melga P, Giusto M, Ciuchi E, Giusti R, Prando R.
Dipartimento di Medicina Interna, Cattedra di Malattie del Ricambio,
Universita degli Studi di Genova.
In the last years the use of alimentary fibres in dietetic management
of diabetic patients increased. The aim of this work was to evaluate,
in type 2 diabetic subjects, the glycaemic and insulinemic increments
after a standard breakfast with glucomannanos enriched biscuits and
with common slices of toast containing the same amounts of carbohydrates
and calories. The basal serum values of glucose and C-peptide were similar
in the two days of the test. The mean increments of glucose and C-peptide
were significantly higher (p < 0.001) after slices of toast than
after glucomannanos enriched biscuits. In conclusion our results show
a reduction in glycaemic increments after breakfast with glucomannanos-biscuits.
The decreased insulin secretion and the reduction of insulin need can
longer preserve the functional reserve of beta-cells.