Effect of glucomannan on obese patients: a clinical study.
Int J Obes. 1984;8(4):289-93.
Walsh DE, Yaghoubian V, Behforooz A.
An eight-week double-blind trial was conducted to test purified glucomannan
fiber as a food supplement in 20 obese subjects. Glucomannan fiber (from
konjac root) or placebo was given in 1-g doses (two 500 mg capsules)
with 8 oz water, 1 h prior to each of three meals per d. Subjects were
instructed not to change their eating or exercise patterns. Results
showed a significant mean weight loss (5.5 lbs) using glucomannan over
an eight-week period. Serum cholesterol and low-density lipoprotein
cholesterol were significantly reduced (21.7 and 15.0 mg/dl respectively)
in the glucomannan treated group. No adverse reactions to glucomannan
Randomized Controlled Trial