| Riv Eur Sci Med Farmacol 1992 Nov-Dec;14(6):367-73
Dietary fiber in the dietetic
therapy of diabetes mellitus. Experimental data with purified
[Article in Italian]
Melga P, Giusto M, Ciuchi E, Giusti R, Prando R.
Dipartimento di Medicina Interna, Cattedra di Malattie del Ricambio,
Universita degli Studi di Genova.
In the last years the use of alimentary fibres in dietetic management
of diabetic patients increased. The aim of this work was to
evaluate, in type 2 diabetic subjects, the glycaemic and insulinemic
increments after a standard breakfast with glucomannanos enriched
biscuits and with common slices of toast containing the same
amounts of carbohydrates and calories. The basal serum values
of glucose and C-peptide were similar in the two days of the
test. The mean increments of glucose and C-peptide were significantly
higher (p < 0.001) after slices of toast than after glucomannanos
enriched biscuits. In conclusion our results show a reduction
in glycaemic increments after breakfast with glucomannanos-biscuits.
The decreased insulin secretion and the reduction of insulin
need can longer preserve the functional reserve of beta-cells.